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Diabetes is a chronic autoimmune disease, which make the body of the sufferer unable to produced or properly use up insulin. In the United

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States of American, there are over 30.3 million sufferers and it is the seventh leading cause of death and number 1 leading cause of kidney failure, lower limb amputations and adult-onset of blindness. Estimated direct and indirect cost of treatment was 245 billion dollars in 2012 an average cost of between $13,700 to $7,900 for each patient (Centers for Disease Control and Prevention, 2017.) While in Europe, there are estimated 53 million adults living with diabetes and the cost of treatment -excluding the complications such as kidney failure, heart disease, amputation etc. - is estimated to cost 9 % of total health expenditure of European countries (International Diabetes Federation Europe & Primary Diabetes Care Europe, 2011.) There are currently no known cures for diabetes diseases. Therefore, proper monitoring of the level of glucose in the blood is fundamental, if the patient is to stay healthy and avoid life-threatening complications that might result from uncontrolled diabetes disease (CDC, 2017.) According to Ginsberg Barry H (2007) blood glucose monitoring is of paramount importance for four reasons: (a) it informs the patient of how much medication (self-adjust insulin) is needed; (b) it provides rough data to the patient on how much they are doing to avoid for example hypoglycemia; (c) it reminds them to change their behaviour to meet their medical need; and (d) it provides data for health care providers to make necessary adjustment of mediation regimen of the patient. The severity of the disease, its prevalence and estimated effects across the globe, highlighted our keen interest in the disease and one of the most modern tools to control the impact.

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Dexcom 5G Mobile CGM work

Can the monitoring device Dexcom G5 Mobile Continuous Glucose Monitoring System (Dexcom G5 Mobile CGM) revolutionize glucose monitoring and set the standard in the near future? Dexcom G5 CGM is the first real-time glucose trends detecting device for adults and children 2 years and older with diabetes. The aim is to detect hyperglycemia (glucose levels too high) and hypoglycemia (glucose levels too low) in real-time with alerts and to help patients to make treatment decisions for example, administer insulin or carbohydrates. It will also facilitate long-time therapy for patients by helping them to determine the patterns in glucose levels. (United States, Food and Drug Administration, FDA 2017.) Dexcom G5 CGM needs prescription and is intended for a single patient use. It consists of a small flexible metal wire sensor (worn subcutaneously for up to 7 days), a transmitter (externally-worn) and a dedicated receiver and/or compatible mobile device. The sensor will respond to the amount of sugar by generating a small electrical signal, which the transmitter will then collect as a glucose value. The transmitter will send the collected values and trends to the receiver every 5 minutes via Bluetooth connection. Before that user must download the application from Android Market or from iTunes App Store and create Dexcom account. Then connect the receiver/mobile device with the transmitter and insert the sensor under the skin. After that user can start receive glucose information. (Dexcom 2017.)

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